Days of rage

Black Rage

If you are attracted to this book by its title you may find it disappointing. It is not about aggression turned outward, about the anger of the blacks, or about the fury which black Americans may vent on the white society they feel oppresses them. Rather, it is a book written by two black psychiatrists about the American Negro's aggression turned inwards?his sense of grief, depression, and self...

RAGE Frameworks

Controlling RAGE

The liver has a finite capacity for regeneration. In mice, removal of 70% of the liver (partial resection) is tolerated but 85% removal (massive resection) is often fatal. Cataldegirmen et al. show on page 473 that blocking RAGE (receptor for advanced glycation end products) allows massively resected mice to survive and regain liver function. Previous studies in mice suggested that recovery aft...

The rage of consent

Concern about the proprietary rights over human body parts has had a dramatic recent impact in some European countries with many implications for future research.

RAGE and soluble RAGE: potential therapeutic targets for cardiovascular diseases.

Receptor for advanced glycation end-products (RAGE) is known to be involved in microvascular complications in diabetes. RAGE is also profoundly associated with macrovascular complications in diabetes through regulation of atherogenesis, angiogenic response, vascular injury, and inflammatory response. The potential significance of RAGE in the pathogenesis of cardiovascular disease appears not to...